Sequence-Dependent Persistence Lengths of DNA

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Sequence-Dependent Persistence Lengths of DNA.

A Monte Carlo code applied to the cgDNA coarse-grain rigid-base model of B-form double-stranded DNA is used to predict a sequence-averaged persistence length of lF = 53.5 nm in the sense of Flory, and of lp = 160 bp or 53.5 nm in the sense of apparent tangent-tangent correlation decay. These estimates are slightly higher than the consensus experimental values of 150 bp or 50 nm, but we believe ...

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ژورنال

عنوان ژورنال: Journal of Chemical Theory and Computation

سال: 2017

ISSN: 1549-9618,1549-9626

DOI: 10.1021/acs.jctc.6b00904